Please use this identifier to cite or link to this item:
https://bibliotecadigital.iue.edu.co/jspui/handle/20.500.12717/2451
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lopera Francisco | - |
dc.date.accessioned | 2021-06-29T00:03:37Z | - |
dc.date.available | 2021-06-29T00:03:37Z | - |
dc.date.issued | 2006-12-20 | - |
dc.identifier.citation | Lopera, et all, F. (2006). Discriminación de factores genéticos en el déficit de atención. Genetic and environmental factors discrimination in attention deficit hyperactivity disorder. Psicoespacios, 1(1), 1-19. https://doi.org/10.25057/21452776.11 | en_ES |
dc.identifier.uri | http://revistas.iue.edu.co/revistasiue/index.php/Psicoespacios/article/view/11 | - |
dc.identifier.uri | http://bibliotecadigital.iue.edu.co/jspui/handle/20.500.12717/2451 | - |
dc.description.abstract | Con el fin deelucidarlos componentes genéticosy ambientales implicadosen la susceptibilidad adesarrollarpor déficit de atencióncon hiperactividad(TDAH), se llevó a caboun análisis de segregación complejaenfamilias nucleares(n= 53) obtenidas de individuos afectadospertenecientes aMedellín, en el Estado de Antioquia, Colombia. Métodosy resultados.Los modelos deefectocohorte (noninheritance), gen multifactorial, mayor recesivo,nonmajorcomponentegenético ynontransmissiondegen mayorfueron rechazadas.Por el contrario,los principales modelosdominantesy codominantesde genes ycomponentesnonmultifactorialno podíaser rechazada.Por lo tanto, el modelo de mejorajuste de los datosera el delgen principal(dominante/codominante). Estegen principalexplica más del99, 99% de la varianza fenotípicaTDAH(valor deheredabilidaden el modelo mixtoigual a0,007%), que permiten suponerunaportebajodel componente ambientalparaelTDAHfenotipo. Frecuencia del gen mayorfue del 3%en la población generalde Antioquia y supenetranciafue cerradoa30%. | en_ES |
dc.format.extent | 19 | en_ES |
dc.format.mimetype | application/pdf | en_ES |
dc.language.iso | spa | en_ES |
dc.publisher | Fondo Editorial Institución Universitaria de Envigado | en_ES |
dc.rights | info:eu-repo/semantics/openAccess | en_ES |
dc.rights.uri | https://creativecommons.org/licenses/by-nd/4.0/ | en_ES |
dc.source | Institución Universitaria de Envigado | en_ES |
dc.source | RI-IUE | en_ES |
dc.title | Discriminación de factores genéticos en el déficit de atención. Genetic and environmental factors discrimination in attention deficit hyperactivity disorder. | en_ES |
oaire.citationendpage | 19 | en_ES |
oaire.citationissue | 1 | en_ES |
oaire.citationstartpage | 1 | en_ES |
oaire.citationvolume | 1 | en_ES |
oaire.version | http://purl.org/coar/version/c_b1a7d7d4d402bcce | en_ES |
dc.identifier.doi | https://doi.org/10.25057/21452776.11 | - |
dc.publisher.faculty | Facultad de Ciencias Sociales | en_ES |
dc.publisher.place | Envigado, Colombia | en_ES |
dc.rights.creativecommons | https://creativecommons.org/licenses/by/4.0/ | en_ES |
dc.subject.keyword | Attention deficit hyperactivity disorder | en_ES |
dc.subject.keyword | major gene | en_ES |
dc.subject.keyword | behavioral genetics | en_ES |
dc.subject.keyword | complex segregation analysis, | en_ES |
dc.subject.keyword | genetics | en_ES |
dc.subject.keyword | multifactoral model | en_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | en_ES |
dc.type.driver | info:eu-repo/semantics/article | en_ES |
dc.type.hasversion | http://purl.org/coar/version/c_b1a7d7d4d402bcce | en_ES |
dc.type.local | Artículo de investigación | en_ES |
dc.type.redcol | https://purl.org/redcol/resource_type/ART | en_ES |
thesis.degree.grantor | Institución Universitaria de Envigado | en_ES |
dc.rights.accessrights | http://purl.org/coar/access_right/c_abf2 | en_ES |
dc.source.tituloRevistaAbreviada | Psicoespacios | en_ES |
dc.subject.proposal | Déficit de Atención e Hiperactividad | en_ES |
dc.subject.proposal | Genética del Comportamiento | en_ES |
dc.subject.proposal | Análisis de Segregación Compleja | en_ES |
dc.subject.proposal | Modelo Multifactorial | en_ES |
dc.subject.proposal | La Genética | en_ES |
dc.subject.proposal | El Gen Principal | en_ES |
dc.description.abstracteng | In order to elucidate the genetic and environmental components involved in the susceptibility to develop attention deficit hyperactivity disorder (ADHD), a complex segregation analysis on nuclear families (n= 53) ascertained from affected probands belonging to Medellín, in the Antioquian State, Colombia, was performed. Methods and results. Models of cohort effect (noninheritance), multifactorial, recessive major gene, nonmajor gene component and nontransmission of major gene were rejected. Contrarily, dominant and codominant major gene models and nonmultifactorial component could not be rejected. Thus, the better model fitting the data was that of the major gene (dominant/codominant). This major gene explains more than 99,99% of the ADHD phenotypic variance (value of heritability in the mixed model equal to 0.007%), which permit to assume a low aport of the environmental component to the phenotype ADHD. Gene frequency of themajor gene was 3% in the general population of Antioquia and its penetrance was closed to 30%. Conclusion. Some cautions and aspects related to the bias of the interview and diagnosis of the parents are discussed [REV NEUROL 1999; 28: 660-4]. | en_ES |
oaire.accessrights | http://purl.org/coar/access_right/c_abf2 | en_ES |
Appears in Collections: | Vol. 01, No. 01: Diciembre 2006 |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
11-Texto del artículo-4571-1-10-20200909.pdf | 349.61 kB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License